What is HCV protein?
The HCV core is a structural protein that aggregates to form the viral capsid, a spherical structure that surrounds and protects the viral genomic RNA. As a component of the nucleocapsid structure, the mature core protein has properties that promote binding to the host-derived lipid membrane and HCV RNA.
What is HCV normal range?
Normal range for this assay is “Not Detected”. The quantitative range of this assay is 10 – 100,000,000 IU/mL (1.0 – 8.0 log IU/mL).
Does HCV go away?
Most people who are infected with hepatitis C don’t experience any symptoms for years. However, hepatitis C usually is a chronic illness (which means it doesn’t go away on its own).
What is the function of the HCV core protein?
Function The HCV core is a structural protein that aggregates to form the viral capsid, a spherical structure that surrounds and protects the viral genomic RNA. The core protein is the first protein to be translated from the HCV genome and together with the envelope glycoproteins (E1 and E2) comprise the three structural HCV proteins.
Which is essential for the replication of HCV?
Among the NS proteins, the NS3 serine-like protease and the RNA-dependent RNA polymerase (RdRp) are essential for viral maturation and replication, and therefore represent ideal targets for the development of small molecule anti-HCV compounds (Figure 1) [ 3, 4 ]. Proteins encoded by the HCV genome.
What kind of RNA does HCV virus have?
HCV is a small enveloped virus with a positive-sense, single-stranded RNA genome that encodes a large polyprotein of 3010 amino acids. The polyprotein is co- and posttranslationally processed by cellular and virally encoded proteases to produce the mature structural and non-structural (NS) proteins.
Which is the first protein translated from the HCV genome?
The HCV core is a structural protein that aggregates to form the viral capsid, a spherical structure that surrounds and protects the viral genomic RNA. The core protein is the first protein to be translated from the HCV genome and together with the envelope glycoproteins (E1 and E2) comprise the three structural HCV proteins.