What drugs have a Chondroprotective effect?
Pentosan polysulfate is a polysulfated polysaccharide drug that acts as a chondroprotective agent. It can: retard the degradation of articular cartilage in osteoarthritis through inhibition of many enzymes that are implicated in the degradation of cartilage.
What are Chondroprotective nutrients?
Chondroprotective nutrients are found in common foods and spices. They are believed to help protect cartilage and joints and include: Compounds derived from green tea. Rosehips.
What are the chondrocytes?
Chondrocytes are the cells responsible for cartilage formation, and they are crucial for the process of endochondral ossification, which is useful for bone development.
What is the articular cartilage?
Articular cartilage is the smooth, white tissue that covers the ends of bones where they come together to form joints. Healthy cartilage in our joints makes it easier to move. It allows the bones to glide over each other with very little friction.
Is a cartilage?
Elastic cartilage is found in the external ear flaps and in parts of the larynx. Hyaline cartilage has fewer cells than elastic cartilage; there is more intercellular space. Hyaline cartilage is found in the nose, ears, trachea, parts of the larynx, and smaller respiratory tubes….
What is meant by Chondroprotective?
From Wikipedia, the free encyclopedia. A chondroprotective compound is a specific compound or chemical that delays progressive joint space narrowing characteristic of arthritis and improves the biomechanics of articular joints by protecting chondrocytes.
Are chondrocytes living?
Chondrocytes (/ˈkɒndrəsaɪt, -droʊ-/, from Greek χόνδρος, chondros = cartilage + κύτος, kytos = cell) are the only cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans….
|Anatomical terms of microanatomy
What is the purpose of chondrocytes?
Chondrocytes in the AC proliferate and secrete extracellular matrix to maintain and sustain the cartilage. The cells themselves are separated from each other by cartilage matrix . They respond to outside stimuli and tissue damage, and are also responsible for degenerative conditions, such as osteoarthritis (OA).
Can you walk with articular cartilage damage?
If left untreated, the joint, especially if it is a weight-bearing one, such as the knee, can eventually become so damaged that the person cannot walk. Apart from immobility, the pain may slowly get worse. All small articular cartilage defects can eventually progress to osteoarthritis if given enough time.
How long does it take to heal articular cartilage damage?
Full recovery from a microfracture technique typically takes at least 6-12 months.