What is Stenotrophomonas infection?
Stenotrophomonas maltophilia is an environmental global emerging Gram-negative MDRO that is most commonly associated with respiratory infections in humans. It can cause various serious infections in humans.
What does Stenotrophomonas maltophilia do?
Stenotrophomonas maltophilia produces proteolytic enzymes and other pathogenic extracellular enzymes such as DNAse, RNAse, elastase, lipase, hyaluronidase, mucinase and hemolysin, which may contribute to the severity of S. maltophilia infection in immunocompromised patients.
How long do you treat Stenotrophomonas?
Learning Objectives: Data on optimal treatment duration for stenotrophomonas maltophilia (S. Maltophilia) pneumonia infections are largely based on anecdotal evidence and case reports. Most cases are treated for 14 to 21 days or longer.
Is Stenotrophomonas infectious?
Conclusion. Stenotrophomonas maltophilia is a globally emerging pathogen that causes serious infectious complications in immunocompromised patients in particular. It also exhibits a wide range of drug resistance mechanisms and this complicates the management of infections caused by this GNB.
Does Stenotrophomonas need isolation?
Although respiratory tract colonisation does not appear to have adverse implications, the isolation of Stenotrophomonas maltophilia indicates a severely compromised host with a high likelihood of mortality attributable to the underlying disease processes.
What antibiotics treat stenotrophomonas Maltophilia?
maltophilia are based on in vitro studies, certain nonrandomized clinical trials, and anecdotal experience. Trimethoprim-sulfamethoxazole remains the drug of choice, although in vitro studies indicate that ticarcillin-clavulanic acid, minocycline, some of the new fluoroquinolones, and tigecycline may be useful agents.