Is Dostinex and cabergoline the same?
Dostinex (cabergoline) is a dopamine receptor antagonist used to treat a hormone imbalance in which there is too much prolactin in the blood (also called hyperprolactinemia).
What medications should not be taken with cabergoline?
Some products that may interact with this drug include: antipsychotic medications (such as chlorpromazine, haloperidol, thiothixene), lorcaserin, metoclopramide, prochlorperazine. Other medications can affect the removal of cabergoline from your body, which may affect how cabergoline works.
What does cabergoline do to the brain?
Cabergoline is a synthetic ergot derived medication that acts on dopamine receptors in the pituitary gland which is located at the base of the brain. Cabergoline stimulates D2 (a specific type of dopamine receptor) receptors in the anterior pituitary gland and prevents the production of the hormone prolactin.
What happens when you stop taking cabergoline?
If you stop taking the drug suddenly or don’t take it at all: The levels of prolactin in your blood will stay high. In women, high prolactin levels can change ovulation, menstrual cycles, and breast milk production. In men, high prolactin levels can affect reproduction and cause sexual issues.
How quickly does cabergoline work?
Cabergoline induced a marked fall in serum PRL which began within 3 h and continued for 7 days. The maximal decrease ranged between -49.2% and -55.2% and occurred after 2-5 days. This maximal effect was only slightly less than that 6 h after bromocriptine treatment (-63.8%).
Why was Dostinex discontinued?
In the 8-week, double-blind period of the comparative trial with bromocriptine, Dostinex (at a dose of 0.5 mg twice weekly) was discontinued because of an adverse event in 4 of 221 patients (2%) while bromocriptine (at a dose of 2.5 mg two times a day) was discontinued in 14 of 231 patients (6%).
Does Dostinex stop breast milk?
Dostinex can also be prescribed to prevent the production of milk in women after birth, if breast-feeding is to be prevented for medical reasons.