What is jakavi used for?

What Jakavi is used for. Jakavi is used to treat adult patients with myelofibrosis, a rare form of blood disorder with a variety of symptoms such as fever, night sweats, bone pain, weight loss. Enlarged spleen is one of the characteristics of myelofibrosis.

Is jakafi chemotherapy?

Jakafi is not chemotherapy. It is a targeted treatment that works to help keep the production of blood cells under control. Discover what may be possible with Jakafi for the treatment of polycythemia vera in patients who did not benefit from HU.

How much does jakavi cost?


Code & Prescriber Medicinal Product Pack (Name, form & strength and pack size) DPMQ
10614P RUXOLITINIB ruxolitinib 5 mg tablet, 56 (PI, CMI) $4911.22
Available brands

Is jakafi better than hydroxyurea?

The researchers concluded that Jakafi provides superior results compared to BAT among patients with PV who have stopped responding to, or are intolerant to hydroxyurea. These results are promising, and provide an effective and well-tolerated treatment option among patients with uncontrolled PV.

How do you take jakavi?

Take Jakafi exactly as instructed by your Healthcare Professional. For most patients, the starting dose of Jakafi is one tablet taken twice a day by mouth. In certain cases, a Healthcare Professional may start a patient at a lower dose or temporarily reduce the dose of Jakafi to once a day.

Does Jakafi lower immune system?

Ruxolitinib is also used to treat a certain problem that may occur after certain stem cell or bone marrow transplants (graft versus host disease). It works by weakening your body’s defense system (immune system).

Does Jakafi weaken your immune system?

What are the final stages of myelofibrosis?

These include anemia, enlarged spleen, blood clotting complications, having too many white blood cells or platelets, and having low platelet counts. Treatments also manage symptoms such as fatigue, night sweats, itchy skin, fever, joint pain, and gout.

How long can you take jakafi?

Jakafi is a long-term treatment. Your Healthcare Professional may allow up to 6 months to see if Jakafi is working for you. If you do not see an improvement after 6 months of treatment, your Healthcare Professional may have you stop taking Jakafi.

How do you get jakafi?

Provider: IncyteCARES Patient Assistance Program (Jakafi)

  1. Must be uninsured or underinsured.
  2. Gross family household income at or less than $125,000 or 600% FPL, whichever is greater.
  3. FDA-approved diagnosis.
  4. Must live in United States or Puerto Rico.
  5. Patient or doctor’s office can call the program to apply.

Can you take jakafi with food?

Jakafi Usage Do not change your dose or stop taking Jakafi without first talking to your healthcare provider. You can take Jakafi with or without food. Jakafi may also be given through certain nasogastric tubes. Tell your healthcare provider if you cannot take Jakafi by mouth.

Can Jakafi cause liver damage?

Ruxolitinib is associated with transient and usually mild elevations in serum aminotransferase during therapy and to rare instances of self-limited, clinically apparent idiosyncratic acute liver injury as well as to cases of reactivation of hepatitis B in susceptible individuals.

What do you need to know about Jakavi?

BAT=best available therapy; CHR=complete haematologic remission; COMFORT=Controlled Myelofibrosis Study with Oral JAK Inhibitor Treatment; ITT=intent to treat; JAK=Janus kinase; QoL=quality of life; STAT=signal transducer and activator of transcription. JAKAVI ® (ruxolitinib) tablets: EU Summary of Product Characteristics. Novartis; May 2019.

What kind of neoplasm is Jakavi approved for?

JAKAVI is the first therapy approved to treat 2 kinds of myeloproliferative neoplasms (MPNs) Approved to treat patients with polycythaemia vera (PV) who are resistant or intolerant to hydroxyurea (HU)

How is Jakavi used in myelofibrosis treatment?

Jakavi contains the active substance ruxolitinib phosphate. This medicine belongs to a group of medicines called Jak inhibitors. Myelofibrosis is a disorder of the bone marrow, in which the marrow is replaced by scar tissue. The abnormal marrow can no longer produce enough normal blood cells and results in a significantly enlarged spleen.

Is it safe to take Jakavi outside the US?

Disclaimer: This is an international website for JAKAVI® (ruxolitinib) and is intended for healthcare professionals outside the US. The information on the site is not country-specific, and may contain information that is outside of the approval in the country in which you are located.