Does Cytoxan have a boxed warning?
Black Box Warnings (abbreviated version): Patients should be closely monitored for bone marrow, liver, kidney & lung toxicity. Methotrexate has been reported to cause fetal death & congenital abnormalities. Not recommended for women of child bearing potential unless the benefits outweigh the risks.
How is Cytoxan supplied?
It is usually given through a vein by injection or infusion (intravenous, IV) or by mouth in tablet form, depending upon diagnosis. Cyclophosphamide is also approved to be given by a shot into a muscle (IM), into the abdominal lining (intraperitoneal, IP), or into the lining of the lung (intrapleural).
What is the brand name for cyclophosphamide?
Cyclophosphamide is the generic name for the trade name drug Cytoxan or Neosar. In some cases, health care professionals may use the trade name Cytoxan or Neosar when referring to the generic drug name cyclophosphamide.
What is cyclophosphamide FDA approved for?
Cyclophosphamide is indicated for the treatment of biopsy proven minimal change nephrotic syndrome in pediatrics patients who failed to adequately respond to or are unable to tolerate adrenocorticosteroid therapy.
How long does Cytoxan stay in the body?
The chemotherapy itself stays in the body within 2 -3 days of treatment but there are short-term and long-term side effects that patients may experience. Not all patients will experience all side effects but many will experience at least a few.
How long does Cytoxan stay in your body?
When cyclophosphamide is given intravenously, the white blood cell count tends to reach its low point (“nadir”) between 7 and 14 days after administration.
Is Cytoxan used to treat lupus?
Cytoxan is a cytotoxic medication usually reserved for lupus patients with serious kidney problems who have not responded to other medications. The dosage of Cytoxan varies from person to person. It can be taken in tablet form, but more often it is given intravenously (IV) at the doctor’s office.
What does Cytoxan do to your body?
It is a chemotherapy drug that works by slowing or stopping cell growth. Cyclophosphamide also works by decreasing your immune system’s response to various diseases. It is used to treat a certain type of kidney disease in children after other treatments have not worked.
What are the long term effects of Cytoxan?
The long-term side effects of cyclophosphamide (Cytoxan) are damage to the bladder and the bone marrow. Bladder cancer is a well-known risk and continues to arise at least 10-15 years after the drug was given.
Is Cytoxan a strong chemo?
Cyclophosphamide, also called Cytoxan, is classified as a “cytotoxic agent”, because it has a toxic effect on many types of cells (“good” cells as well as “bad”). Cyclophosphamide is one of a number of medications first developed as a chemotherapy drug (a medication used in the treatment of cancer).
What is Cytoxan used for?
Cytoxan is actually a cancer drug, but in lupus patients, it’s used to treat serious kidney inflammation (including lupus nephritis ) or other complications that threaten the organs.
What happens during Cytoxan treatment?
Cytoxan is a therapy that may be given to people with multiple sclerosis. It works by suppressing the immune system. It’s given to people with MS because the disease is thought to be the result of an abnormally active and misdirected, immune system.
Is Cytoxan an immunosuppressive medication?
Cyclophosphamide (Cytoxan®) Originally developed as a chemotherapy drug (to treat cancer) and used as an immunosuppressant (to treat lupus). Taken in pill form previously. Today, Cytoxan is taken through the vein (intravenously, or IV).
Does Cytoxan cause kidney damage?
Acute kidney failure is found among people who take Cytoxan, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Zometa , and have Osteoporosis.