Why is apixaban better?
“This study shows apixaban is a better option for oral anticoagulation than warfarin because it reduces stroke while substantially reducing intracranial haemorrhage,” said lead author Renato D. Lopes, MD, PhD, a cardiologist at Duke Clinical Research Institute.
What are nursing considerations for apixaban?
- Educate patients about signs and symptoms of bleeding and bleeding precautions.
- Instruct patients not to double up on dosing in an attempt to make up a missed dose.
- Stress to patients the importance of informing healthcare providers that they’re taking apixaban due to increased bleeding risk.
What should be monitored when taking apixaban?
An anticoagulant helps to prevent clots from forming in the blood. While you are on this medication you will need to be watched carefully for bleeding and bruising. Your health care provider will work with you to keep you safe and healthy while you are taking apixaban (ELIQUIS®).
How effective is apixaban?
Apixaban was as effective as dabigatran and rivaroxaban in reducing thromboembolic events and stroke. The risk of major bleeding was significantly lower for apixaban compared with warfarin, dabigatran, and rivaroxaban (relative risk reduction, 38%, 35%, and 46%, respectively).
What painkillers can you take while on apixaban?
Taking apixaban with everyday painkillers You can take paracetamol while you’re taking apixaban. Do not take aspirin or ibuprofen while you’re taking apixaban unless a doctor has said it’s OK to. They increase the chance of bleeding.
What can you not take with apixaban?
You can take paracetamol while you’re taking apixaban. Do not take aspirin or ibuprofen while you’re taking apixaban unless a doctor has said it’s OK to. They increase the chance of bleeding.
What did the NICE Appraisal Committee consider about apixaban?
4.1 The Appraisal Committee reviewed the data available on the clinical and cost effectiveness of apixaban, having considered evidence on the nature of non-valvular atrial fibrillation and the value placed on the benefits of apixaban by people with the condition, those who represent them, and clinical specialists.
How many patients have been treated with apixaban?
3.3 In AMPLIFY, the efficacy population was defined as the intention‑to‑treat population for whom the outcome status at 6 months was documented (this comprised 2609 patients in the apixaban arm and 2635 patients in the enoxaparin/warfarin arm).
Is it safe to take apixaban for stroke?
The safety of apixaban was maintained across patients at different levels of stroke risk, regardless of warfarin control (time in therapeutic range) and in patients who needed dose reduction.
How are apixaban and warfarin meta analyses done?
The manufacturer used a Bayesian Markov chain Monte Carlo stimulation in WinBUGS to conduct 2 network meta-analyses using a fixed-effect model. The first meta-analysis included patients for whom vitamin K antagonist treatment was suitable and it compared apixaban, warfarin, dabigatran and rivaroxaban.