What is a parallel group design?

Definition. A parallel group design is an experimental study design in which each subject is randomized to one of two or more distinct treatment/intervention groups. Those who are assigned to the same treatment are referred to as a treatment group.

What is parallel group technique?

A parallel design, also called a parallel group study, compares two or more treatments. Participants are randomly assigned to either group, treatments are administered, and then the results are compared. This randomization reduces the risk of erroneous results (i.e. statistical bias).

What is parallel design RCT?

Parallel group trial design. Parallel arm design is the most commonly used study design. In this design, subjects are randomized to one or more study arms and each study arm will be allocated a different intervention.

What is parallel assignment in clinical trial?

Parallel assignment. A type of intervention model describing a clinical trial in which two or more groups of participants receive different interventions. For example, a two-arm parallel assignment involves two groups of participants. One group receives drug A, and the other group receives drug B.

How many groups are compared in parallel group design?

A parallel study is a type of clinical study where two groups of treatments, A and B, are given so that one group receives only A while another group receives only B. Other names for this type of study include “between patient” and “non-crossover”.

What is two pair Group design?

two-pair group design. This design is an elaboration of the two group design wherein there are two experimental groups and two control groups. parallel-group design. Design in which two or more groups are used at the same time with only one single variable manipulated or changed.

What is the goal of parallel design?

Parallel design allows for: A range of ideas to be generated quickly and cost effectively. Several approaches to be explored at the same time, thus compressing the concept development schedule. Concepts generated to be combined so that the final solution benefits from all ideas proposed.

What type of study is RCT?

A randomized controlled trial (RCT) is an experimental form of impact evaluation in which the population receiving the programme or policy intervention is chosen at random from the eligible population, and a control group is also chosen at random from the same eligible population.

What are the different types of RCT?

Depending on the extent of blinding, RCTs can be classified as open, single-blind, double-blind, triple-blind, and quadruple-blind. What is an open RCT? An open RCT is a randomised trial in which everybody involved in the trial knows which intervention is given to each participant.

Is parallel or crossover better?

The advantage of a parallel design is that it provides the best way to assess the effect of a drug on survival, if that is the critical endpoint in its evaluation. Second, optimal crossover studies are statistically efficient and thus require fewer subjects than do non-crossover designs.

What is the difference between a parallel design and a cross over design?

The way the groups get compared varies, depending on the study design. The most common design is called a parallel study. Participants are randomly assigned to treatment arms. This approach randomly assigns participants to one group, who then “crossover” to another treatment arm during the course of the trial.

What are the different types of parallel group designs?

Basically there are two types of parallel group design for comparative clinical trials, namely, group comparison (or parallel-group) designs and matched pairs parallel designs. The simplest group comparison parallel group design is the two-group parallel design which compares two treatments (e.g., a treatment group vs. a control group).

How are parallel groups used in clinical trials?

Parallel Group Designs. A parallel group design is a complete randomized design in which each patient receives one and only one treatment in a random fashion. Basically there are two types of parallel group design for comparative clinical trials, namely, group comparison (or parallel-group) designs and matched pairs parallel designs.

Which is better matched pairs or parallel groups?

As compared to parallel group designs, matched pairs parallel group designs can reduce variability from treatment comparison. In addition a matched pairs parallel group design requires a smaller patient population. Therefore it is considered a more suitable design for progressive diseases such as cancer.

Why are parallel group designs not independent estimates?

In other words, the observed variability for any comparisons between groups contains both interpatient and intrapatient variabilities that cannot be separated and estimated due to the nature of the parallel group design. As a result a parallel design does not provide independent estimates of the interpatient and intrapatient variabilities.