Is amiodarone oral or IV?

ACUTE TREATMENT 2,10 In patients who require long-term treatment, intravenous dosing should be switched to oral dosing. Patients who received intravenous amiodarone for less than one week should take 800 to 1,600 mg oral amiodarone per day.

How will the intravenous administration be converted to oral administration?

Intravenous-to-oral (IV-to-PO [per oral]) switch therapy is a treatment procedure to convert the administration of medication from intravenous to oral. The procedure involves starting hospitalized patients on an initial intravenous therapy and stepping it down to oral therapy as early as possible.

How do you install amiodarone oral?


  1. Load: 800-1600 mg PO qDay for 1-3 weeks until response; once adequate arrhythmia control achieved, reduce dose to 600-800 mg/day for 1 mo; THEN reduce to maintenance dose.
  2. Maintenance dose: 400 mg PO qDay.

Can amiodarone be given orally?

Amiodarone oral tablet is available as a generic drug and as a brand-name drug. Brand name: Pacerone. Amiodarone is also available as a solution for injection. You may start with the oral tablet in the hospital and continue to take the tablet at home.

Why is intravenous better than oral?

Using oral rather than parenteral antibiotics Major advantages of oral over the intravenous route are the absence of cannula-related infections or thrombophlebitis, a lower drug cost, and a reduction in hidden costs such as the need for a health professional and equipment to administer intravenous antibiotics.

Is ceftriaxone IV or PO?

Rocephin is a sterile, semisynthetic, broad-spectrum cephalosporin antibiotic for intravenous or intramuscular administration.

Is amiodarone hard on the kidneys?

Amiodarone is well known for a myriad of side effects, some severe and life-threatening, including pulmonary toxicity, hepatotoxicity, and thyrotoxicity. One of the organs which could be affected by Amiodarone is Kidney, which, fortunately, is not a common occurrence.

How dangerous a drug is amiodarone?

Amiodarone may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

How to administer Amiodarone IV?

Dosing. To prepare Amiodarone for an IV infusion, mix with D5W and give through an in-line filter. Alternatively, it is NOT necessary to dilute amiodarone for IV push administration and a filter is not necessary. When infusions exceed 2 hours, amiodarone can absorb into the plastic used for standard IV bags.

What should I avoid while taking amiodarone?

Amiodarone may be taken with or without food but should be taken at the same way each time. You should avoid consuming grapefruits and grapefruit juice while taking amiodarone. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

Which are the safer alternatives to amiodarone?

Dronedarone has been viewed as a potential therapeutic alternative for amiodarone because of a lower risk for pulmonary, thyroid, and dermatologic adverse effects. Compared with amiodarone, dronedarone has poor bioavailability and a shorter terminal disposition half-life, which dictates a twice-daily dosing regimen.